Chemical Biology in the HUB at the Novartis Campus September 19 2024

Chemical Biology in The HUB Symposium

This sixth-in-a-series of scientific talks will focus on cutting edge research in Chemical Biology from both academic and industry labs in the areas of translational chemical biology, machine learning, novel target identification and validation, chemical imaging, as well as new chemical modalities.

This day-long symposium will be followed by a reception with appetizers and refreshments for the symposium speakers and attendees.

We wish to thank all of the sponsors and volunteers from industry who are making this possible. Our sponsors include, in alphabetical order, Arrakis Therapeutics, AstraZeneca, Biogen, BMS, C4 Therapeutics, FogPharma, GSK, Jnana Therapeutics, Kymera Therapeutics, Matchpoint Therapeutics, Merck, Northeastern Section of the ACS, Novartis, Pfizer, Sanofi, Scorpion Therapeutics, Vertex. Our organizers are pleased to continue this fall tradition this year and in the coming years; please be in contact with us (below) if you are interested in participating in future symposia through volunteering, through sponsorship, or other means.

Please note: we expect these tickets to sell out. Industry tickets are available in two waves (labeled: day 1 and day 2 – just denoting the day they go on sale). Thursday, August 22 at noon and Friday, August 23 at 5 pm. You may join the waitlist after the day 1 tickets sell out, but you should try to purchase in the second wave. Only one waitlist exists – that on the first industry ticket wave.

Registration is required and a ticket will be necessary for admission to the symposium and the networking reception

Schedule of Events

8:00 – 9:00 AM Registration and coffee

9:00 – 9:05 AM Opening remarks

9:05 – 9:45 AM Bridget Wagner, Arena BioWorks

New targets in the beta cell discovered through phenotypic screening

9:45 – 10:15 AM Wankyu Lee, AstraZeneca

Leveraging Chemical Biology and Proteomics to Impact Projects at AstraZeneca

10:15 – 10:35 AM Coffee Break

10:35 – 11:15 AM Christine Mayr, Sloan Kettering Institute

TBD

11:15 – 11:45 AM Jeff Martin, Biogen

Chemoproteomic Selectivity Profiling of Clinical BTK Inhibitors Reveals an Off-Target with Potential Implications for DILI

11:45 am – 12:30 PM Lunch

12:30 – 1:10 PM Jonathan Ostrem, UCSF

TBD

1:10 – 1:40 PM Jaimeen Majmudar, Pfizer

A covalent, allele specific monovalent degrader for the treatment of MAFLD

1:40 – 2:20 PM Raymond Moellering, University of Chicago

TBD

2:20 – 2:45 PM Coffee break

2:45 – 3:15 PM Serene Keilani and Xiaoqing Han, Merck

Discovering Therapeutic Targets in Human Macrophages Using Novel Phenotypic Screening Techniques

3:15 – 3:45 PM Jonathan Solomon, Novartis

Beyond the beta turn: A novel structural motif bound by a CRBN glue degrader

3:45 – 4:30 PM Jim Wells, UCSF

Discovering cell surface neighborhoods in cancer

4:30 – 4:35 PM Closing remarks

4:35 – 6:00 PM Poster session and reception

Questions? Please contact: Jason Thomas, jason.thomas@novartis.com

THE PUBLIC IS INVITED – RESERVATIONS ARE REQUIRED

FAQs

There are several buildings on the Novartis campus. The symposium will be held on the original 250 Massachusetts Ave Campus, which is directly across from the more recent 181 Massachusetts Ave Campus. The original 250 Massachusetts Ave Campus is located on the same side of the street as Flour and Roxy’s Arcade.

What are my transport/parking options getting to the event?

The Novartis campus is located in Central Square and is walking distance from the Central Square or Kendall Square T-stops of the Red Line. There are also numerous parking garages in the area.

For driving directions from where you will begin your trip, enter “250 Massachusetts Ave, Cambridge, MA 02139”

Is my registration/ticket transferrable?

Yes, please contact Jason Thomas before September 12, 2024.